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1

Sepsis and septic shock

Hotchkiss, Richard S., Moldawer, Lyle L., Opal, Steven M., Reinhart, Konrad, Turnbull, Isaiah R., Vincent, Jean-Louis

Journal:

Nature Reviews Disease Primers

Year:

2016

Language:

english

File:

PDF, 878 KB

english, 2016

2

The Pathophysiology and Treatment of Sepsis

Hotchkiss, Richard S., Karl, Irene E.

Journal:

Boston Medical and Surgical Journal

Year:

2003

Language:

english

File:

PDF, 353 KB

english, 2003

3

Out-of-pocket payments and utilization of health care services in Albania: Evidence from three districts

David Richards Hotchkiss, Paul Lawrence Hutchinson, Altin Malaj, Andrés Alejandro Berruti

Journal:

Year:

2005

Language:

english

File:

PDF, 186 KB

english, 2005

4

Stress-induced fractal rearrangement of the endothelial cell cytoskeleton causes apoptosis

Susan L. DeMeester, J.Perren Cobb, Richard S. Hotchkiss, Dale F. Osborne, Irene E. Karl, Kevin W. Tinsley, Timothy G. Buchman

Journal:

Year:

1998

Language:

english

File:

PDF, 365 KB

english, 1998

5

TAT-Bim Induces Extensive Apoptosis in Cancer Cells

Hiroyuki Kashiwagi, Jonathan E. McDunn, Peter S. Goedegebuure, Mary C. Gaffney, Katherine Chang, Kathryn Trinkaus, David Piwnica-Worms, Richard S. Hotchkiss, William G. Hawkins

Journal:

Annals of Surgical Oncology

Year:

2007

Language:

english

File:

PDF, 466 KB

english, 2007

6

Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach

Hotchkiss, Richard S, Monneret, Guillaume, Payen, Didier

Journal:

The Lancet Infectious Diseases

Year:

2013

Language:

english

File:

PDF, 821 KB

english, 2013

7

Understanding why clinicians should care about danger-associated molecular patterns

Asehnoune, Karim, Hotchkiss, Richard S., Monneret, Guillaume

Journal:

Intensive Care Medicine

Year:

2016

Language:

english

File:

PDF, 1018 KB

english, 2016

8

Desperate Times Call for Desperate Measures

Crouser, Elliott D., Hotchkiss, Richard S.

Journal:

Critical Care Medicine

Year:

2017

Language:

english

File:

PDF, 379 KB

english, 2017

9

Host-directed therapies for bacterial and viral infections

Kaufmann, Stefan H. E., Dorhoi, Anca, Hotchkiss, Richard S., Bartenschlager, Ralf

Journal:

Nature Reviews Drug Discovery

Year:

2017

Language:

english

File:

PDF, 1.19 MB

english, 2017

10

Immunotherapy: It is not just for cancer anymore

Moldawer, Lyle L., Hotchkiss, Richard

Journal:

Journal of Leukocyte Biology

Year:

2018

Language:

english

File:

PDF, 153 KB

english, 2018

11

Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab

Hotchkiss, Richard S., Colston, Elizabeth, Yende, Sachin, Crouser, Elliott D., Martin, Greg S., Albertson, Timothy, Bartz, Raquel R., Brakenridge, Scott C., Delano, Matthew J., Park, Pauline K., Donni

Journal:

Intensive Care Medicine

Year:

2019

Language:

english

File:

PDF, 810 KB

english, 2019

12

What Is the Skinny on Obesity During Sepsis?*

Crouser, Elliott D., Caldwell, Charles C., Hotchkiss, Richard S.

Journal:

Critical Care Medicine

Year:

2019

File:

PDF, 183 KB

2019

13

An Aspirin a Day Keeps the Intensivist Away?*

Turnbull, Isaiah R., Hotchkiss, Richard S.

Journal:

Critical Care Medicine

Year:

2019

File:

PDF, 58 KB

2019

14

Lighting the Dark: Evolution of the Postinflationary Universe

Musoke, Nathan, Hotchkiss, Shaun, Easther, Richard

Journal:

Physical Review Letters

Year:

2020

File:

PDF, 564 KB

2020

15

Activating Immunity to Fight a Foe â A New Path

Phimister, Elizabeth G., Hotchkiss, Richard S., Opal, Steven M.

Journal:

New England Journal of Medicine

Year:

2020

Language:

english

File:

PDF, 3.91 MB

english, 2020

16

Ultrastructure of a primary fibrosarcoma of the human thyroid gland

Woo-Yung Shin, Belinde Aftalion, Edward Hotchkiss, Richard Schenkman, James Berkman

Journal:

Year:

1979

Language:

english

File:

PDF, 3.46 MB

english, 1979

17

Bim–Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis

John C. Scatizzi, Jack Hutcheson, Richard M. Pope, Gary S. Firestein, Alisa E. Koch, Melissa Mavers, Avraham Smason, Hemant Agrawal, G. Kenneth Haines III, Navdeep S. Chandel, Richard S. Hotchkiss, Ha

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 596 KB

english, 2010

18

Oncogenic T-antigen of JC virus is present frequently in human gastric cancers

Sung Kwan Shin, Mei-Shu Li, Florentine Fuerst, Erin Hotchkiss, Richard Meyer, Tae Kim II, Ajay Goel, C. Richard Boland

Journal:

Year:

2006

Language:

english

File:

PDF, 301 KB

english, 2006

19

Targeting AKT with the proapoptotic peptide, TAT-CTMP: A novel strategy for the treatment of human pancreatic adenocarcinoma

Peter O. Simon Jr., Jonathan E. McDunn, Hiroyuki Kashiwagi, Katherine Chang, Peter S. Goedegebuure, Richard S. Hotchkiss, William G. Hawkins

Journal:

International Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 695 KB

english, 2009

20

De novo constitutional MLH1 epimutations confer early-onset colorectal cancer in two new sporadic Lynch syndrome cases, with derivation of the epimutation on the paternal allele in one

Ajay Goel, Thuy-Phuong Nguyen, Hon-Chiu E. Leung, Takeshi Nagasaka, Jennifer Rhees, Erin Hotchkiss, Mildred Arnold, Pia Banerji, Minoru Koi, Chau-To Kwok, Deborah Packham, Lara Lipton, C. Richard Bola

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 1.69 MB

english, 2011

21

Concurrent quantification of tissue metabolism and blood flow via 2h/31P NMR in vivo. i. assessment of absolute metabolite quantification

Sheng-kwei Song, Richard S. Hotchkiss, Joseph J. H. Ackerman

Journal:

Magnetic Resonance in Medicine

Year:

1992

Language:

english

File:

PDF, 638 KB

english, 1992

22

Concurrent quantification of tissue metabolism and blood flow via 2h/31P NMR in Viva iii. alterations of muscle blood flow and metabolism during sepsis

Sheng-Kwei Song, Richard S. Hotchkiss, Irene E. Karl, Joseph J. H. Ackerman

Journal:

Magnetic Resonance in Medicine

Year:

1992

Language:

english

File:

PDF, 654 KB

english, 1992

23

Amadori ketoses with calcium hydroxide and the Kiliani reaction on 1-deoxy ketoses: two approaches to the synthesis of saccharinic acids

David J. Hotchkiss, Sarah F. Jenkinson, Richard Storer, Thomas Heinz, George W.J. Fleet

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 126 KB

english, 2006

24

Sepsis Increases Intracellular Free Calcium in Brain

Stasia A. Anderson, Sheng-Kwei Song, Joseph J. H. Ackerman, Richard S. Hotchkiss

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 282 KB

english, 1999

25

The use of wetlands (dambos) for micro-scale irrigation in Zimbabwe

Robert A. Lambert, Patricia F. Hotchkiss, Neil Roberts, Richard D. Faulkner, Morag Bell, Alan Windram

Journal:

Irrigation and Drainage Systems

Year:

1990

Language:

english

File:

PDF, 664 KB

english, 1990

26

Lactate dehydrogenase as a predictor of kidney involvement in patients with sickle cell anemia

Sevgi Gurkan, Kyla J. Scarponi, Hilary Hotchkiss, Beth Savage, Richard Drachtman

Journal:

Pediatric Nephrology

Year:

2010

Language:

english

File:

PDF, 109 KB

english, 2010

27

Biosynthesis of Medium-chain-length Poly(hydroxyalkanoates) from Soy Molasses

Daniel K. Y. Solaiman, Richard D. Ashby, Arland T. Hotchkiss, Thomas A. Foglia

Journal:

Biotechnology Letters

Year:

2006

Language:

english

File:

PDF, 203 KB

english, 2006

28

Sepsis induces extensive autophagic vacuolization in hepatocytes: a clinical and laboratory-based study

Watanabe, Eizo, Muenzer, Jared T, Hawkins, William G, Davis, Christopher G, Dixon, David J, McDunn, Jonathan E, Brackett, Daniel J, Lerner, Megan R, Swanson, Paul E, Hotchkiss, Richard S

Journal:

Laboratory Investigation

Year:

2009

Language:

english

File:

PDF, 800 KB

english, 2009

29

Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms

Saleh, Maya, Vaillancourt, John P., Graham, Rona K., Huyck, Matthew, Srinivasula, Srinivasa M., Alnemri, Emad S., Steinberg, Martin H., Nolan, Vikki, Baldwin, Clinton T., Hotchkiss, Richard S.

Journal:

Year:

2004

Language:

english

File:

PDF, 340 KB

english, 2004

30

The sepsis seesaw: tilting toward immunosuppression

Hotchkiss, Richard S, Coopersmith, Craig M, McDunn, Jonathan E, Ferguson, Thomas A

Journal:

Nature Medicine

Year:

2009

Language:

english

File:

PDF, 162 KB

english, 2009

31

Apoptosis and caspases regulate death and inflammation in sepsis

Hotchkiss, Richard S., Nicholson, Donald W.

Journal:

Nature Reviews Immunology

Year:

2006

Language:

english

File:

PDF, 539 KB

english, 2006

32

Effect of cold preservation on intracellular calcium concentration and calpain activity in rat sinusoidal endothelial cells

G.Aravinda Upadhya, Stefan A. Topp, Richard S. Hotchkiss, John Anagli, Steven M. Strasberg

Journal:

Year:

2003

Language:

english

File:

PDF, 638 KB

english, 2003

33

Lymphocyte phenotype distinguishes septic from nonseptic critical illness

Steven J. Schwulst, Jared Muenzer, Katherine Chang, Richard Hotchkiss

Journal:

Journal of the American College of Surgeons

Year:

2006

Language:

english

File:

PDF, 60 KB

english, 2006

34

Splenic CD4+ T Cells Have a Distinct Transcriptional Response Six Hours after the Onset of Sepsis

Jonathan E. McDunn, Isaiah R. Turnbull, Ashoka D. Polpitiya, Alice Tong, Sandra K. MacMillan, Dale F. Osborne, Richard S. Hotchkiss, Marco Colonna, J. Perren Cobb

Journal:

Journal of the American College of Surgeons

Year:

2006

Language:

english

File:

PDF, 2.84 MB

english, 2006

35

Molecular Diagnostics in Sepsis: From Bedside to Bench

T. Philip Chung, Jason M. Laramie, Donald J. Meyer, Thomas Downey, Laurence H.Y. Tam, Huashi Ding, Timothy G. Buchman, Irene Karl, Gary D. Stormo, Richard S. Hotchkiss, J. Perren Cobb

Journal:

Journal of the American College of Surgeons

Year:

2006

Language:

english

File:

PDF, 1.31 MB

english, 2006

36

Lymphocyte Phenotyping to Distinguish Septic from Nonseptic Critical Illness

Steven J. Schwulst, Jared T. Muenzer, Katherine C. Chang, Tejal S. Brahmbhatt, Craig M. Coopersmith, Richard S. Hotchkiss

Journal:

Journal of the American College of Surgeons

Year:

2008

Language:

english

File:

PDF, 460 KB

english, 2008

37

siRNA targeted at pro-apoptotic proteins, PUMA and BIM, inhibits sepsis-induced lymphocyte apoptosis

Pavan Brahmamdam, Katherine C. Chang, Ryan K. Zeidan, Shyam M. Rele, Yongchao Liang, Joanna Y. Liu, Jeremy D. Heidel, Jonathan E. McDunn, Craig M. Coopersmith, Richard S. Hotchkiss

Journal:

Journal of the American College of Surgeons

Year:

2008

Language:

english

File:

PDF, 49 KB

english, 2008

38

Blocking programmed death-1 inhibits lymphocyte apoptosis and improves survival in intraabdominal sepsis

Pavan Brahmamdam, Katherine C. Chang, Dale F. Osborne, Richard S. Hotchkiss

Journal:

Journal of the American College of Surgeons

Year:

2009

Language:

english

File:

PDF, 92 KB

english, 2009

39

BH3-only proteins have differential roles in hepatic ischemia-reperfusion injury

Bernard John DuBray, Parvathi Balachandran, Brett L. Knolhoff, Gundumi A. Upadhya, Jianluo Jia, Richard S. Hotchkiss, Thallachallour Mohanakumar, William C. Chapman, Christopher D. Anderson

Journal:

Journal of the American College of Surgeons

Year:

2011

Language:

english

File:

PDF, 95 KB

english, 2011

40

Cecal ligation and puncture followed by MRSA pneumonia increases mortality in mice and blunts production of local and systemic cytokines

Erin E. Perrone, Enjae Jung, Jessica A. Dominguez, Andrew T. Clark, Amy C. Fox, W. Michael Dunne, Richard S. Hotchkiss, Craig M. Coopersmith

Journal:

Journal of the American College of Surgeons

Year:

2011

Language:

english

File:

PDF, 94 KB

english, 2011

41

CHOP mediates cold ischemia and reperfusion injury in steatotic hepatocytes

Parvathi Balachandran, Bernard J. Dubray, Richard S. Hotchkiss, Jianluo Jia, Brett Knolhoff, Gundumi A. Upadhya, Thalachallour Mohanakumar, William C. Chapman, Christopher D. Anderson

Journal:

Journal of the American College of Surgeons

Year:

2011

Language:

english

File:

PDF, 63 KB

english, 2011

42

Respiratory sensitization and allergy: Current research approaches and needs

Darrell R. Boverhof, Richard Billington, B. Bhaskar Gollapudi, John A. Hotchkiss, Shannon M. Krieger, Alan Poole, Connie M. Wiescinski, Michael R. Woolhiser

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 328 KB

english, 2008

43

Confocal fluorescent intravital microscopy of the murine spleen

Mitchell H Grayson, David D Chaplin, Irene E Karl, Richard S Hotchkiss

Journal:

Journal of Immunological Methods

Year:

2001

Language:

english

File:

PDF, 622 KB

english, 2001

44

265: Microalbuminuria and Lactate Dehydrogenase (LDH) as Predictors of Kidney Involvement in a Pediatric Sickle Cell Disease (SCD) Population

Kyla J. Scarponi, Hilary Hotchkiss, Beth Savage, Richard Drachtman, Sevgi Gurkan

Journal:

American Journal of Kidney Diseases

Year:

2010

Language:

english

File:

PDF, 87 KB

english, 2010

45

MANKIND, ITS NUMBERS, HEALTH, AND FAMILY ARRANGEMENTS: GROUP REPORT 3

Emily H. Mudd, Carl E. Taylor, Lorenz K. Y. Ng, Rollin D. Hotchkiss, Richard A. Prindle, Stacey B. Day, Anneta Duveen

Journal:

Annals of the New York Academy of Sciences

Year:

1975

Language:

english

File:

PDF, 651 KB

english, 1975

46

NADPH Oxidase of Neutrophils Elevates o,o′-Dityrosine Cross-Links in Proteins and Urine during Inflammation

Suchandra Bhattacharjee, Subramaniam Pennathur, Jaeman Byun, Jan Crowley, Dianne Mueller, Jennifer Gischler, Richard S. Hotchkiss, Jay W. Heinecke

Journal:

Archives of Biochemistry and Biophysics

Year:

2001

Language:

english

File:

PDF, 169 KB

english, 2001

47

Direct measurement of nitric oxide in headspace gas produced by a chicken macrophage cell line in a closed culture system

Yen-Jen Sung, Joseph H. Hotchkiss, Richard E. Austic, Rodney R. Dietert

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 459 KB

english, 1992

48

Adoptive transfer of dying cells causes bystander-induced apoptosis

Steven J. Schwulst, Christopher G. Davis, Craig M. Coopersmith, Richard S. Hotchkiss

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 464 KB

english, 2007

49

Anti-apoptotic peptides protect against radiation-induced cell death

Kevin W. McConnell, Jared T. Muenzer, Kathy C. Chang, Chris G. Davis, Jonathan E. McDunn, Craig M. Coopersmith, Carolyn A. Hilliard, Richard S. Hotchkiss, Perry W. Grigsby, Clayton R. Hunt

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 227 KB

english, 2007

50

Iron Dysregulation Combined with Aging Prevents Sepsis-Induced Apoptosis1

Pardis Javadi, Timothy G. Buchman, Paul E. Stromberg, Isaiah R. Turnbull, Dinesh Vyas, Richard S. Hotchkiss, Irene E. Karl, Craig M. Coopersmith

Journal:

Journal of Surgical Research

Year:

2005

Language:

english

File:

PDF, 516 KB

english, 2005